Foundations
Where to start
What a peptide actually is, how they get studied, and the vocabulary you need before any paper makes sense. No assumed background.
Private community
Search any peptide and you get two kinds of result: shops, and papers written for people who already know the field. Neither one helps you decide anything. This is where the research gets read properly, with the terminology explained and the weak studies called weak.
Hosted on Skool.
Material you work through at your own pace, and people to ask when it stops making sense.
Foundations
What a peptide actually is, how they get studied, and the vocabulary you need before any paper makes sense. No assumed background.
Method
Sample size, controls, who funded it, and why a result in twelve mice is not a result in you. This part stays useful long after you have forgotten the specifics.
Community
Questions answered by people willing to say nobody knows yet, which turns out to be the honest answer more often than the internet admits.
Claims
How a small finding becomes a headline and then a product page. Watch that happen a few times and it stops working on you.
Five papers worth your evening, and the reason we would rather you read them than take our word for anything.
The trial the headlines came from. 338 adults, 48 weeks, dose-dependent results. Phase 2 means it has not yet been through the larger confirmatory stage.
(opens PubMed in a new tab) Tirzepatide Tirzepatide Once Weekly for the Treatment of ObesitySURMOUNT-1. A phase 3 trial, which is a materially stronger kind of evidence than the row above it — worth reading the two side by side for exactly that reason.
(opens PubMed in a new tab) Semaglutide Once-Weekly Semaglutide in Adults with Overweight or ObesitySTEP 1. The trial behind the drug most people have heard of, and a useful baseline for judging every claim made since.
(opens PubMed in a new tab) Tesamorelin Body composition, hepatic fat, metabolic and safety outcomes of tesamorelin in HIV-associated lipodystrophyA meta-analysis of a peptide that is actually approved, for one narrow indication. Approval is specific, never general.
(opens PubMed in a new tab) BPC-157 Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic ReviewRead this one last. Of 36 included studies, 35 were preclinical and one was clinical. A peptide can be everywhere online and still have almost no human evidence behind it.
(opens PubMed in a new tab)Every link goes to PubMed, where the abstract is free to read. Listing a study is not a recommendation of anything in it, and a paper existing is not the same as a question being settled.
Peps by Dave is an educational community. The material is for general information only. It is not medical advice, not a diagnosis, and not a treatment plan, and it is no substitute for talking to a qualified healthcare professional who knows your history.
We do not provide dosing or administration guidance. Many peptides are not approved for human use in most jurisdictions and are sold for laboratory research only. What is legal is your responsibility to establish where you live.
Never start, stop or change anything you are taking based on something you read in a community. Talk to your doctor.
The material, the papers, and somewhere to ask when a study stops making sense.
Hosted on Skool. Questions first? Email pepsbydave@gmail.com.